Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486910 | 0.91 | HDAC1 (0.32) | — | |
| SCHEMBL8483473 | 0.89 | TOP2A (0.42) | TOP2A | |
| SCHEMBL8482764 | 0.88 | TOP2A (0.34) | TOP2A | |
| SCHEMBL8483307 | 0.87 | THRB (0.37) | TOP2AMAPT | |
| SCHEMBL8485863 | 0.86 | TOP2A (0.43) | TOP2AMAPT | |
| SCHEMBL8486549 | 0.83 | DYRK1A (0.36) | TOP2A | |
| SCHEMBL8483655 | 0.82 | — | — | |
| SCHEMBL8486876 | 0.77 | THRB (0.37) | TOP2AMAPT | |
| SCHEMBL8486373 | 0.77 | KMT2A (0.33) | MAPT | |
| SCHEMBL8485927 | 0.77 | TOP2A (0.47) | TOP2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935969-A | Pyrido-thiopyrandoinazoles with antitumor activity | UNIVERSITY OF VERMONT (US) | 1999-08-10 | — | — | US | disclosed |