Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
| ▸ | SI | P14410 | 2/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1873215 | 0.85 | GAA (0.50) | TSHRALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL1876364 | 0.83 | NAAA (0.39) | TSHRALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL1880735 | 0.81 | TSHR (0.42) | TSHRALDH1A1TDP1GAAPRKCA | |
| SCHEMBL28378728 | 0.81 | ALDH1A1 (0.38) | TSHRALDH1A1GAAHTTRECQL | |
| SCHEMBL99435 | 0.81 | TSHR (0.48) | TSHRALDH1A1CYP3A4GAAHTT | |
| SCHEMBL19399320 | 0.80 | — | — | |
| SCHEMBL13502967 | 0.79 | TSHR (0.33) | TSHRGAAHTTRECQLHSD17B10 | |
| SCHEMBL27984925 | 0.79 | TSHR (0.46) | TSHRALDH1A1CYP3A4GAAHTT | |
| SCHEMBL1879588 | 0.78 | NAAA (0.48) | TSHRALDH1A1TDP1L3MBTL1 | |
| SCHEMBL1881180 | 0.75 | LMNA (0.42) | TSHRALDH1A1GAAHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919753-A | Cross-linking agent | NYCOMED IMAGING AS (NO) | 1999-07-06 | — | — | US | disclosed |
| US-5693321-A | Polymers containing diester units | NYCOMED IMAGING AS (NO) | 1997-12-02 | — | — | US | disclosed |
| US-5534250-A | METHYLENE DIESTER GROUPS, BIODEGRADABLE | NYCOMED IMAGING AS (NO) | 1996-07-09 | — | — | US | disclosed |
| EP-0547126-B1 | BIODEGRADABLE POLYMERS CONTAINING DIESTER UNITS | NYCOMED IMAGING AS (NO) | 1996-02-28 | — | — | EP | disclosed |
| EP-0547126-A1 | POLYMERS CONTAINING DIESTER UNITS. | NYCOMED IMAGING AS (NO) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004392-A1 | POLYMERS CONTAINING DIESTER UNITS | HOLMES, MICHAEL, JOHN (GB) | 1992-03-19 | — | — | WO | disclosed |