Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5829437 | 0.84 | SLC6A3 (0.48) | SLC6A3MTNR1AMTNR1BRECQLPPARG | |
| SCHEMBL31170906 | 0.84 | SLC6A3 (0.48) | SLC6A3MTNR1AMTNR1BRECQLPPARG | |
| SCHEMBL7398621 | 0.82 | ROCK2 (0.51) | SLC6A3RECQLPPARGPPARDPPARA | |
| SCHEMBL5257603 | 0.82 | KMT2A (0.55) | MTNR1AMTNR1B | |
| SCHEMBL28595878 | 0.80 | MTNR1A (0.46) | UTS2RSLC6A3MTNR1AMTNR1BAKR1C3 | |
| SCHEMBL19986352 | 0.80 | SLC6A3 (0.51) | UTS2RSLC6A3EDNRA | |
| SCHEMBL631558 | 0.78 | SLC6A3 (0.50) | SLC6A3 | |
| SCHEMBL28601751 | 0.78 | MTNR1A (0.46) | UTS2RSLC6A3MTNR1AMTNR1B | |
| SCHEMBL7336112 | 0.77 | SLC6A3 (0.50) | SLC6A3RECQLPPARGPPARDPPARA | |
| SCHEMBL30992200 | 0.77 | SLC6A3 (0.45) | SLC6A3RECQLPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863917-A | ANXIOLYTIC AGENT, ANTICONVULSANTS, ANALGESICS AND NEUROPROTECTIVES. | PFIZER, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| WO-1997031902-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-09-04 | — | — | WO | disclosed |
| EP-0792874-A1 | Quinoxaline derivatives useful in therapy | Pfizer Limited (GB) | 1997-09-03 | — | — | EP | disclosed |