Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.45 |
| ▸ | PTGES | O14684 | 10/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488768 | 0.91 | DYRK3 (0.41) | RXFP1PTGESRAF1AURKAAURKB | |
| SCHEMBL6537820 | 0.86 | RXFP1 (0.45) | RXFP1KCNK3KCNK9PTGESF2R | |
| SCHEMBL8486940 | 0.84 | PTGES (0.45) | RXFP1KCNK3KCNK9PTGESTP53 | |
| SCHEMBL6538002 | 0.83 | RXFP1 (0.45) | RXFP1KCNK3KCNK9PTGESF2R | |
| SCHEMBL8489178 | 0.82 | MAPT (0.45) | MAPT | |
| SCHEMBL6538197 | 0.82 | PTGES (0.43) | RXFP1PTGESF2RTP53MAPT | |
| SCHEMBL6537426 | 0.82 | PTGES (0.50) | RXFP1PTGES | |
| SCHEMBL8486693 | 0.80 | GSK3A (0.41) | RAF1MAPT | |
| SCHEMBL8490008 | 0.78 | MAPT (0.43) | AURKBMAPT | |
| SCHEMBL8489721 | 0.78 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021835-A1 | QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |