Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | USP28 | Q96RU2 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491881 | 0.88 | LMNA (0.42) | LMNAPDK1PDK2PDK3PDK4 | |
| SCHEMBL8607107 | 0.85 | LMNA (0.39) | LMNAPDK1PDK2PDK3PDK4 | |
| SCHEMBL8489240 | 0.83 | GPR119 (0.38) | LMNAPDK1PDK2PDK3PDK4 | |
| SCHEMBL8492581 | 0.81 | GPR119 (0.33) | LMNAALDH1A1CYP2C19KMT2AMAPT | |
| SCHEMBL8491698 | 0.75 | IKBKB (0.35) | ALDH1A1GPR119 | |
| SCHEMBL8494434 | 0.71 | HPD (0.46) | LMNAMEN1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL1016807 | 0.70 | LMNA (0.59) | LMNAPDK1PDK2PDK3PDK4 | |
| SCHEMBL8493162 | 0.70 | HPD (0.57) | MEN1ALDH1A1CYP2C19KMT2AMAPT | |
| SCHEMBL8110000 | 0.70 | GPR119 (0.43) | GPR119 | |
| SCHEMBL8494506 | 0.68 | LMNA (0.35) | LMNAALDH1A1CYP2C19KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066439-C | Method for prepn. of isoxazoles herbicides | RHONE POULENC AGROCHIMIE (GB) | 2001-05-30 | — | — | CN | disclosed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| CN-1037058-C | Herbicide composition and use thereof | RHONE POULENC AGRICULTURE (GB) | 1998-01-21 | — | — | CN | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| CN-1141294-A | Method for prepn. of isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-01-29 | — | — | CN | disclosed |
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |