Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488569 | 0.84 | MTNR1A (0.55) | MTNR1ASLC6A4 | |
| SCHEMBL5521083 | 0.77 | NR3C1 (0.44) | PARP1HTR2AHTR2CKDM4C | |
| SCHEMBL12388673 | 0.75 | PARP1 (0.59) | PARP1HCRTR1HCRTR2 | |
| SCHEMBL28330085 | 0.73 | PARP1 (0.49) | PARP1HTR2AHTR2CMTNR1AKDM4C | |
| SCHEMBL17362144 | 0.73 | PARP1 (0.49) | PARP1MTNR1AKDM4CKCNH2CCR8 | |
| SCHEMBL8489943 | 0.73 | ALDH1A1 (0.36) | MTNR1AEEDALDH1A1GAA | |
| SCHEMBL6680529 | 0.73 | PARP1 (0.46) | PARP1 | |
| SCHEMBL6680532 | 0.73 | PARP1 (0.46) | PARP1 | |
| SCHEMBL3364106 | 0.72 | PARP1 (0.49) | PARP1HTR2AHTR2CMTNR1AKDM4C | |
| SCHEMBL10275022 | 0.72 | PARP1 (0.45) | PARP1HTR2AHTR2CMTNR1AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |