Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29011945 | 0.95 | HTT (0.59) | HTTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5315574 | 0.90 | HAO1 (0.59) | ALDH1A1KMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL7814223 | 0.87 | CNR2 (0.53) | HTTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL3380070 | 0.86 | MAOA (0.58) | HTTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL26085763 | 0.86 | RAB9A (0.64) | ALDH1A1KMT2AMEN1RAB9AHPGD | |
| SCHEMBL7811166 | 0.84 | HAO1 (0.54) | HTTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7813763 | 0.84 | MEN1 (0.57) | NPSR1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11757663 | 0.83 | HAO1 (0.50) | HTTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7810437 | 0.82 | HAO1 (0.46) | HTTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7814092 | 0.82 | ACHE (0.47) | HTTNPSR1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972950-A | ANTIINFLAMMATORY AND ANALGESIC AGENT | LABORATORIES UPSA (FR) | 1999-10-26 | — | — | US | disclosed |
| WO-1998015528-A1 | NOVEL DIARYLMETHYLENE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USES THEREOF | LABORATOIRES UPSA (FR) | 1998-04-16 | — | — | WO | disclosed |