Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021891 | 0.81 | HDAC3 (0.52) | GAAKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL4342180 | 0.79 | ESR2 (0.56) | ALDH1A1NPC1RAB9AMEN1POLB | |
| SCHEMBL20108460 | 0.79 | ALDH1A1 (0.72) | TSHRALDH1A1NPC1RAB9APOLB | |
| SCHEMBL9372218 | 0.78 | TSHR (1.00) | TSHRALDH1A1MEN1POLBGAA | |
| SCHEMBL7022742 | 0.77 | ESR2 (0.47) | ALDH1A1NPC1RAB9AGAAKMT2A | |
| SCHEMBL14744445 | 0.76 | RORC (0.71) | RORC | |
| SCHEMBL28466152 | 0.76 | LTB4R2 (0.52) | TSHRALDH1A1POLBHDAC3HDAC4 | |
| SCHEMBL2183716 | 0.75 | ALDH1A1 (0.76) | ALDH1A1SOAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL16495929 | 0.75 | TSHR (0.46) | TSHRRORCESR2 | |
| SCHEMBL11660177 | 0.74 | ALDH1A1 (0.73) | ALDH1A1SOAT1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439261-B2 | Process for the preparation of valsartan and intermediates thereof | DIPHARMA S.P.A. (IT) | 2008-10-21 | — | — | US | disclosed |
| EP-1533305-A1 | A process for the preparation of valsartan and intermediates thereof | Dipharma S.p.A. (IT) | 2005-05-25 | — | — | EP | disclosed |