Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487218 | 1.00 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL8491771 | 0.96 | SIGMAR1 (0.35) | MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL8491780 | 0.88 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8485655 | 0.87 | S1PR1 (0.36) | SIGMAR1 | |
| SCHEMBL8490617 | 0.87 | S1PR1 (0.36) | SIGMAR1 | |
| SCHEMBL8489660 | 0.85 | — | — | |
| SCHEMBL8486397 | 0.85 | — | — | |
| SCHEMBL8489937 | 0.82 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL8488573 | 0.81 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL8488600 | 0.75 | PER2 (0.38) | MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919431-A | 1,4,7,10-tetraazacyclododecane derivatives, their use, pharmaceutical agents containing these compounds and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-07-06 | — | — | US | disclosed |