Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491963 | 0.84 | L3MBTL1 (0.48) | TDP1L3MBTL1HDAC1HDAC7TSHR | |
| Leucine SCHEMBL6412363 | 0.82 | MMP1 (0.53) | ELANETDP1L3MBTL1MMP2MMP3 | |
| Leucine SCHEMBL8524451 | 0.80 | MMP1 (0.47) | ELANETDP1L3MBTL1MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL7156167 | 0.72 | HDAC1 (0.56) | ELANETDP1L3MBTL1HDAC1HDAC7 | |
| SCHEMBL29166106 | 0.72 | HDAC7 (0.53) | TDP1HDAC1HDAC7 | |
| SCHEMBL9856551 | 0.71 | PPARG (0.48) | MMP2GRIK1 | |
| SCHEMBL9191639 | 0.70 | HDAC1 (0.52) | TDP1L3MBTL1MMP2HDAC1HDAC7 | |
| SCHEMBL6843799 | 0.69 | TDP1 (0.58) | TDP1L3MBTL1HDAC1HDAC7TSHR | |
| Hydrochloric Acid SCHEMBL9394212 | 0.69 | HDAC1 (0.51) | ELANETDP1L3MBTL1MMP2HDAC1 | |
| SCHEMBL11481918 | 0.69 | HDAC1 (0.58) | TDP1L3MBTL1HDAC1HDAC7MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932551-A | INHIBITORS OF MATRIX METALLOENDOPROTEINASE-MEDIATED DISEASES | MERCK & CO., INC. (US) | 1999-08-03 | — | — | US | disclosed |