Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL8488907 | 0.84 | ELANE (0.44) | L3MBTL1TDP1HDAC1HDAC7CASP3 | |
| SCHEMBL7329031 | 0.76 | TDP1 (0.49) | L3MBTL1TDP1HDAC1HDAC7CASP3 | |
| SCHEMBL6578347 | 0.75 | TDP1 (0.51) | L3MBTL1TDP1HDAC1HDAC7CASP3 | |
| Leucine SCHEMBL8524451 | 0.74 | MMP1 (0.47) | L3MBTL1TDP1 | |
| SCHEMBL8966420 | 0.74 | ALDH1A1 (0.50) | L3MBTL1TDP1MAPK1ALDH1A1 | |
| SCHEMBL5019164 | 0.74 | ALDH1A1 (0.50) | L3MBTL1TDP1MAPK1ALDH1A1 | |
| SCHEMBL1245400 | 0.74 | ALDH1A1 (0.50) | L3MBTL1TDP1MAPK1ALDH1A1 | |
| SCHEMBL408911 | 0.73 | TDP1 (0.49) | L3MBTL1TDP1HDAC1HDAC7CASP3 | |
| Hydrochloric Acid SCHEMBL29131620 | 0.73 | ALDH1A1 (0.49) | L3MBTL1TDP1MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL14119382 | 0.73 | ALDH1A1 (0.49) | L3MBTL1TDP1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932551-A | INHIBITORS OF MATRIX METALLOENDOPROTEINASE-MEDIATED DISEASES | MERCK & CO., INC. (US) | 1999-08-03 | — | — | US | disclosed |