SCHEMBL8488982

SCHEMBL8488982

O=[C]c1cccc(OCc2ccccc2)c1OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ALPG P10696 1/20 0.45
PTK2B Q14289 1/20 0.45
HTR1A P08908 6/20 0.45
DRD2 P14416 1/20 0.45
CCNB2 O95067 1/20 0.44
CDK1 P06493 1/20 0.44
CDK4 P11802 1/20 0.44
CCNB1 P14635 1/20 0.44
CCND1 P24385 1/20 0.44
CCNB3 Q8WWL7 1/20 0.44
LIPE Q05469 1/20 0.44
ADRA1D P25100 5/20 0.43
ADRA1A P35348 5/20 0.43
ADRA1B P35368 5/20 0.43
LTA4H P09960 1/20 0.42
MAPK14 Q16539 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2248786 0.86 MAPT (0.53) MAPTMAPK1TDP1L3MBTL1ALPG
SCHEMBL15602827 0.83 SGMS2 (0.52) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL6215213 0.82 MAPT (0.67) MAPTMAPK1TDP1L3MBTL1ALPG
SCHEMBL7293348 0.75 MAPT (0.44) MAPTMAPK1TDP1L3MBTL1ALPG
SCHEMBL5666449 0.74 LMNA (0.46) MAOB
SCHEMBL8352651 0.74 NPC1 (0.49) MAPTL3MBTL1MAOB
SCHEMBL1766179 0.74 MAPT (0.56) MAPTMAPK1TDP1L3MBTL1ALPG
SCHEMBL1952684 0.74 HTR1A (0.63) MAPTMAPK1TDP1L3MBTL1ALPG
SCHEMBL19612456 0.74 HTR1A (0.63) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL18623128 0.74 HTR1A (0.68) MAPTMAPK1TDP1L3MBTL1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999042435-A2 MYXOCHELINES ANALYTICON AG BIOTECHNOLOGIE PHARMAZIE (DE) 1999-08-26 WO disclosed