Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488165 | 0.82 | SLC6A2 (0.42) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL8489231 | 0.81 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA2 | |
| SCHEMBL8076992 | 0.77 | CHRNA7 (0.46) | CHRNB2CHRNA4CHRNA7ALDH1A1CHRNB4 | |
| SCHEMBL30116774 | 0.77 | CHRNA7 (0.46) | CHRNB2CHRNA4CHRNA7ALDH1A1CHRNB4 | |
| SCHEMBL8488486 | 0.75 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA2 | |
| SCHEMBL8484697 | 0.75 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA2 | |
| SCHEMBL8487566 | 0.75 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNA7CHRNA3 | |
| SCHEMBL8488006 | 0.74 | SLC6A2 (0.44) | — | |
| SCHEMBL8487483 | 0.73 | MDM2 (0.39) | TSHRTHPO | |
| SCHEMBL8488675 | 0.73 | SLC6A3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999038865-A1 | 8-AZABICYCLO(3.2.1)OCT-2-ENE DERIVATIVES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-08-05 | — | — | WO | disclosed |