Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489089 | 0.84 | HTR2C (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8488006 | 0.84 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8488992 | 0.82 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL8487483 | 0.82 | MDM2 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8488675 | 0.82 | SLC6A3 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8487415 | 0.82 | SLC6A3 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8485877 | 0.80 | HTR2C (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8489231 | 0.77 | CHRNB2 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8489583 | 0.75 | ALDH1A1 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8525323 | 0.73 | TRIM24 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999038865-A1 | 8-AZABICYCLO(3.2.1)OCT-2-ENE DERIVATIVES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-08-05 | — | — | WO | disclosed |