Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683983 | 0.87 | DHODH (0.36) | DHODHKIF18APDE2ANPC1LMNA | |
| SCHEMBL8493300 | 0.87 | DHODH (0.36) | DHODHKIF18APDE2ANPC1LMNA | |
| SCHEMBL2778848 | 0.86 | PAK1 (0.42) | NPC1LMNARAB9AMEN1KMT2A | |
| SCHEMBL8492055 | 0.86 | NR1I2 (0.39) | DHODHCRACR2A | |
| SCHEMBL8495014 | 0.85 | DHODH (0.34) | DHODHKIF18APDE2ANPC1LMNA | |
| SCHEMBL8493270 | 0.84 | DHODH (0.34) | DHODHKIF18APDE2ANPC1LMNA | |
| SCHEMBL8494493 | 0.84 | IRAK4 (0.39) | DHODHLMNARAB9AMEN1KMT2A | |
| SCHEMBL6912863 | 0.84 | CACNA1B (0.42) | DHODHKIF18ACRACR2A | |
| SCHEMBL8492350 | 0.83 | LMNA (0.50) | DHODHNPC1LMNARAB9AMEN1 | |
| SCHEMBL7573465 | 0.83 | DHODH (0.33) | DHODHKIF18APDE2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |