Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495014 | 0.91 | DHODH (0.34) | DHODHMEN1KMT2AKIF18APDE2A | |
| SCHEMBL6054845 | 0.87 | DHODH (0.33) | DHODHMAPK1PDE2A | |
| SCHEMBL7573670 | 0.87 | SLC6A9 (0.35) | DHODHPDE2ALMNA | |
| SCHEMBL8890658 | 0.86 | PTGS2 (0.40) | MAPK1MEN1KMT2A | |
| SCHEMBL7575701 | 0.85 | HCRTR2 (0.40) | DHODHPDE2ALMNA | |
| SCHEMBL7576300 | 0.85 | DHODH (0.46) | DHODHMEN1KMT2ANPC1LMNA | |
| SCHEMBL8891685 | 0.84 | PTGS2 (0.38) | MAPK1MEN1KMT2A | |
| SCHEMBL8891642 | 0.84 | ALDH1A1 (0.39) | MAPK1MEN1KMT2A | |
| SCHEMBL8683983 | 0.84 | DHODH (0.36) | DHODHKMT2AKIF18APDE2ANPC1 | |
| SCHEMBL8493300 | 0.84 | DHODH (0.36) | DHODHKIF18APDE2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | claimed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | claimed |
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |