Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573465 | 0.91 | DHODH (0.33) | DHODHMEN1KMT2AKIF18APDE2A | |
| SCHEMBL8890658 | 0.88 | PTGS2 (0.40) | MEN1KMT2APTGS1PTGS2ALDH1A1 | |
| SCHEMBL8891642 | 0.86 | ALDH1A1 (0.39) | TRPM8MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL8891685 | 0.86 | PTGS2 (0.38) | MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL8493300 | 0.86 | DHODH (0.36) | DHODHALDH1A1KIF18APDE2ANPC1 | |
| SCHEMBL8683983 | 0.86 | DHODH (0.36) | DHODHKMT2AKIF18APDE2ANPC1 | |
| SCHEMBL8890712 | 0.85 | KDM4E (0.34) | PTGS1PTGS2KIF18APDE2ANPC1 | |
| SCHEMBL8894099 | 0.85 | PTGS2 (0.40) | MEN1KMT2APTGS2ALDH1A1NPC1 | |
| SCHEMBL8818315 | 0.85 | KAT7 (0.37) | MEN1KMT2AKIF18APDE2A | |
| SCHEMBL8492055 | 0.85 | NR1I2 (0.39) | DHODHPTGS2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | claimed |
| EP-0527037-B1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-10-16 | — | — | EP | claimed |
| CN-1069267-A | HERBICIDE | RHONE POULENC AGRICULTURE (GB) | 1993-02-24 | — | — | CN | claimed |
| EP-0527037-A1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-02-10 | — | — | EP | claimed |
| CN-1042334-C | Herbicide composition containing 4-benzoyl isoxazole derivative and application thereof | RHONE POULENC AGRICULTURE (GB) | 1999-03-03 | — | — | CN | disclosed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| CN-1141295-A | Prepn. method for 4-benzoyl isoxazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1997-01-29 | — | — | CN | disclosed |
| EP-0527037-B1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995022903-A1 | NEW PESTICIDAL METHOD | RHONE-POULENC AGROCHIMIE (FR) | 1995-08-31 | — | — | WO | disclosed |
| CN-1069267-A | HERBICIDE | RHONE POULENC AGRICULTURE (GB) | 1993-02-24 | — | — | CN | disclosed |
| EP-0527037-A1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-02-10 | — | — | EP | disclosed |