Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.34 |
| ▸ | PPARG | P37231 | 11/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466886 | 0.71 | TRPA1 (0.30) | — | |
| SCHEMBL8489503 | 0.71 | CDC7 (0.30) | — | |
| SCHEMBL7207522 | 0.65 | MEN1 (0.31) | — | |
| SCHEMBL8489924 | 0.62 | TRPA1 (0.34) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8617142 | 0.62 | MEN1 (0.30) | — | |
| SCHEMBL1253523 | 0.57 | SLC6A4 (0.54) | PPARAPPARGSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3037011 | 0.57 | SLC6A2 (0.61) | PPARAPPARGSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17045248 | 0.57 | SLC6A4 (0.67) | PPARAPPARGSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17045245 | 0.57 | SLC6A4 (0.67) | PPARAPPARGSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19616116 | 0.57 | SLC6A4 (0.54) | PPARAPPARGSLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958965-A | TREATMENT OF DISEASES ATTENDING DISTURBANCES IN THE SEROTINERGIC SYSTEMS, SUCH AS ANXIETY, STRESS, DEPRESSION, SEXUAL DYSFUNCTIONS AND SLEEP DISTURBANCES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-28 | — | — | US | claimed |
| US-5958965-A | TREATMENT OF DISEASES ATTENDING DISTURBANCES IN THE SEROTINERGIC SYSTEMS, SUCH AS ANXIETY, STRESS, DEPRESSION, SEXUAL DYSFUNCTIONS AND SLEEP DISTURBANCES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-28 | — | — | US | disclosed |
| US-5817690-A | ANTIDOPAMINE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |