Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489924 | 0.90 | TRPA1 (0.34) | — | |
| SCHEMBL8617142 | 0.90 | MEN1 (0.30) | — | |
| SCHEMBL8492022 | 0.90 | LTA4H (0.34) | DAO | |
| SCHEMBL7207522 | 0.71 | MEN1 (0.31) | — | |
| SCHEMBL8489752 | 0.68 | GPR84 (0.38) | CDC7DBF4 | |
| SCHEMBL8620184 | 0.68 | NQO2 (0.35) | — | |
| SCHEMBL7207966 | 0.64 | KMT2A (0.51) | — | |
| SCHEMBL8489926 | 0.62 | PPARA (0.34) | — | |
| SCHEMBL27769455 | 0.57 | ALDH1A1 (0.59) | — | |
| SCHEMBL9153358 | 0.57 | IDO1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958965-A | TREATMENT OF DISEASES ATTENDING DISTURBANCES IN THE SEROTINERGIC SYSTEMS, SUCH AS ANXIETY, STRESS, DEPRESSION, SEXUAL DYSFUNCTIONS AND SLEEP DISTURBANCES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-28 | — | — | US | claimed |
| US-5958965-A | TREATMENT OF DISEASES ATTENDING DISTURBANCES IN THE SEROTINERGIC SYSTEMS, SUCH AS ANXIETY, STRESS, DEPRESSION, SEXUAL DYSFUNCTIONS AND SLEEP DISTURBANCES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-28 | — | — | US | disclosed |
| US-5817690-A | ANTIDOPAMINE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |