Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 5/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654857 | 0.73 | FFAR1 (0.53) | RAB9APOLBLMNAMAPTKDM4E | |
| SCHEMBL8487082 | 0.73 | FFAR1 (0.40) | RAB9AALDH1A1LMNAMAPTMAPK8 | |
| SCHEMBL6651458 | 0.73 | F10 (0.49) | RAB9APOLBLMNAMAPTKDM4E | |
| SCHEMBL27874835 | 0.72 | GAA (0.55) | RAB9AALDH1A1POLBLMNAKDM4E | |
| SCHEMBL6560595 | 0.71 | RORC (0.47) | RAB9APOLBRORCLMNAMAPT | |
| SCHEMBL8490597 | 0.71 | RORC (0.44) | RAB9AALDH1A1POLBRORCLMNA | |
| SCHEMBL29815800 | 0.70 | CYP11B1 (0.56) | RAB9APOLBLMNAMAPTKDM4E | |
| SCHEMBL3174815 | 0.70 | CYP11B1 (0.56) | RAB9APOLBLMNAMAPTKDM4E | |
| SCHEMBL8069562 | 0.69 | MAPK8 (0.47) | RAB9APOLBRORCLMNAMAPT | |
| SCHEMBL17052990 | 0.68 | CYP2A6 (0.52) | RAB9AALDH1A1LMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008366-A | REACTING A ACYLATED 5-AMINOISOTHIAZOLE WITH A HALOGENATING OR NITRATING AGENTS IN PRESENCE OF DILUENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-28 | — | — | US | disclosed |
| US-5972843-A | FOR CONTROLLING INSECTS, ARACHNIDS AND NEMATODES, WHICH ARE ENCOUNTERED IN AGRICULTURE, IN FORESTRY, IN THE PROTECTION OF STORED PRODUCTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |