Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IL18 | Q14116 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069562 | 0.78 | MAPK8 (0.47) | RORCKDM4EMEN1LMNAPOLB | |
| SCHEMBL8490597 | 0.75 | RORC (0.44) | RORCLMNAPOLBMAPTPKM | |
| SCHEMBL6906376 | 0.74 | CACNA1H (0.48) | KDM4EMEN1LMNAPOLBMAPT | |
| SCHEMBL8988057 | 0.73 | MAPK10 (0.48) | RORCKDM4EMEN1LMNAPOLB | |
| SCHEMBL11564197 | 0.71 | RAB9A (0.54) | KDM4EMEN1LMNAPOLBMAPT | |
| SCHEMBL8490231 | 0.71 | RIPK1 (0.43) | RORCKDM4EMEN1LMNAPOLB | |
| SCHEMBL6271911 | 0.70 | ICAM1 (0.38) | RORCKDM4EMEN1LMNAPOLB | |
| SCHEMBL8987819 | 0.70 | MAPK10 (0.45) | RORCKDM4EMEN1LMNAPOLB | |
| SCHEMBL7336030 | 0.69 | SCN9A (0.55) | SCN9A | |
| SCHEMBL6917099 | 0.69 | SRD5A2 (0.57) | KDM4EMEN1LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861241-B1 | ACYLATED 5-AMINOISOTHIAZOLES WITH INSECTICIDAL PROPERTIES, INTERMEDIATE PRODUCTS AND PROCESS FOR PRODUCING THEM | BAYER CROPSCIENCE AG (DE) | 2004-04-14 | — | — | EP | disclosed |
| US-6008366-A | REACTING A ACYLATED 5-AMINOISOTHIAZOLE WITH A HALOGENATING OR NITRATING AGENTS IN PRESENCE OF DILUENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-28 | — | — | US | disclosed |
| US-5972843-A | FOR CONTROLLING INSECTS, ARACHNIDS AND NEMATODES, WHICH ARE ENCOUNTERED IN AGRICULTURE, IN FORESTRY, IN THE PROTECTION OF STORED PRODUCTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |
| EP-0861241-A1 | ACYLATED 5-AMINOISOTHIAZOLES WITH INSECTICIDAL PROPERTIES, INTERMEDIATE PRODUCTS AND PROCESS FOR PRODUCING THEM | BAYER AG (DE) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997018198-A1 | ACYLATED 5-AMINOISOTHIAZOLES WITH INSECTICIDAL PROPERTIES, INTERMEDIATE PRODUCTS AND PROCESS FOR PRODUCING THEM | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-22 | — | — | WO | disclosed |