Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 8/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IL18 | Q14116 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094492 | 0.86 | MAPK8 (0.41) | MAPK8MAPK9MAPK10KDM4EGLS | |
| SCHEMBL7233873 | 0.83 | MAPK8 (0.54) | MAPK8MAPK9MAPK10KDM4EMEN1 | |
| SCHEMBL8104093 | 0.82 | KMT2A (0.49) | MAPK8MEN1LMNAPOLBMAPT | |
| SCHEMBL8094581 | 0.81 | SMN1; SMN2 (0.40) | MAPK8MAPK9MAPK10KDM4EMEN1 | |
| SCHEMBL7232438 | 0.79 | GLS (0.43) | MAPK8KDM4ELMNAPOLBMAPT | |
| SCHEMBL6560595 | 0.78 | RORC (0.47) | MAPK8CACNA1HKDM4EMEN1LMNA | |
| SCHEMBL7998311 | 0.78 | GLS (0.44) | MAPK8KDM4EPOLBMAPTRAB9A | |
| SCHEMBL6906376 | 0.77 | CACNA1H (0.48) | CACNA1HKDM4EMEN1LMNAPOLB | |
| SCHEMBL8094494 | 0.76 | MAPK8 (0.44) | MAPK8LMNAMAPTRAB9ARORC | |
| SCHEMBL8490597 | 0.76 | RORC (0.44) | MAPK8LMNAPOLBMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005461-A1 | ACYLATED 5-AMINOISOTHIAZOLES AS PESTICIDES AND FUNGICIDES | Bayer Aktiengesellschaft (DE) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999010334-A1 | ACYLATED 5-AMINOISOTHIAZOLES AS PESTICIDES AND FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-04 | — | — | WO | disclosed |