Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | GHSR | Q92847 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27403391 | 1.00 | KMT2A (0.64) | KMT2AMEN1HCRTR1TDP1KCNA5 | |
| SCHEMBL19392083 | 1.00 | KMT2A (0.64) | KMT2AMEN1HCRTR1TDP1KCNA5 | |
| SCHEMBL9845636 | 0.91 | GHSR (0.55) | KMT2AMEN1HCRTR1KCNA5MAPT | |
| SCHEMBL10587595 | 0.88 | OPRM1 (0.53) | KMT2AMEN1HCRTR1KCNA5MAPT | |
| SCHEMBL24425711 | 0.87 | ALOX15 (0.62) | KMT2AMEN1MAPTOPRM1GHSR | |
| SCHEMBL18625067 | 0.87 | KMT2A (0.58) | KMT2AMEN1HCRTR1MAPTOPRM1 | |
| SCHEMBL10796218 | 0.86 | KCNA5 (0.57) | KMT2AMEN1HCRTR1KCNA5MAPT | |
| SCHEMBL14446809 | 0.86 | TACR1 (0.62) | KMT2AMEN1MAPTTP53 | |
| SCHEMBL5613868 | 0.86 | KMT2A (0.67) | KMT2AMEN1HCRTR1TDP1KCNA5 | |
| SCHEMBL120493 | 0.86 | ALOX15 (0.67) | KMT2AMEN1MAPTALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981755-A | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| US-5716979-A | NONPEPTIDES, UNIQUE IN ALKYLATION/SUBSTITUTION PATTERN ALONG THEIR BACKBONE, USEFUL FOR TREATING DISORDERS SUCH AS RESPIRATORY, INFLAMMATORY, GASTROINTESTINAL, OPHTHALMIC, ALLERGIES, PAIN, VASCULAR, MIGRANE, ARTHRITIS AND BRAIN | WARNER-LAMBERT COMPANY (US) | 1998-02-10 | — | — | US | disclosed |
| US-5594022-A | CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1994004494-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |