Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylsulfane SCHEMBL2473223 | 0.66 | KCNH2 (0.45) | ALDH1A1L3MBTL1HPGDMAPTTUBB4A | |
| SCHEMBL10355248 | 0.64 | MAPT (0.46) | ALDH1A1POLBLMNAKDM4EHPGD | |
| SCHEMBL8562378 | 0.63 | DHFR (0.45) | DHFRALDH1A1POLBTDP1LMNA | |
| Hydrochloric Acid SCHEMBL10355455 | 0.63 | MAPT (0.45) | ALDH1A1POLBLMNAKDM4EHPGD | |
| SCHEMBL10355310 | 0.62 | MAPT (0.51) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10355429 | 0.61 | MAPT (0.50) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL11386138 | 0.60 | L3MBTL1 (0.44) | DHFRL3MBTL1TYMS | |
| Diphenylsulfane SCHEMBL28115694 | 0.58 | SLC6A4 (0.47) | DHFRALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL1879820 | 0.58 | BCHE (0.59) | ALDH1A1POLBTDP1LMNAKDM4E | |
| SCHEMBL30831170 | 0.58 | BCHE (0.59) | ALDH1A1POLBTDP1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999006377-A1 | DERIVATIVES OF 1-((3,3-DIMETHYL-3-SILABUTOXY)METHYL)-2-(PHENYLSULFONYL)IMIDAZOLE | GLIATECH, INC. (US) | 1999-02-11 | — | — | WO | disclosed |