SCHEMBL1879820

SCHEMBL1879820

c1ccc(Sc2nc3ccccc3[nH]2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.59
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
KDM4E B2RXH2 2/20 0.58
ALDH1A1 P00352 2/20 0.58
MAPT P10636 1/20 0.58
STAT3 P40763 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
RAB9A P51151 4/20 0.57
NPC1 O15118 4/20 0.57
POLB P06746 1/20 0.56
AR P10275 3/20 0.56
TXN P10599 2/20 0.54
SMN1; SMN2 Q16637 5/20 0.53
EPHX2 P34913 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30831170 1.00 BCHE (0.59) BCHEKMT2AMEN1KDM4EALDH1A1
SCHEMBL3792726 0.88 BCHE (0.68) BCHEKMT2AMEN1KDM4EALDH1A1
SCHEMBL31325602 0.86 NPC1 (0.61) BCHEKMT2AMEN1KDM4EALDH1A1
SCHEMBL8566169 0.86 BCHE (0.53) BCHEKMT2AMEN1KDM4EALDH1A1
SCHEMBL14112761 0.86 ALDH1A1 (0.60) BCHEKMT2AMEN1KDM4EALDH1A1
SCHEMBL17821366 0.82 MYC (0.54) BCHEKMT2AMEN1KDM4EALDH1A1
SCHEMBL8558318 0.80 MAPT (0.66) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL29798184 0.80 HPGD (0.53) BCHEKMT2AMEN1KDM4EALDH1A1
SCHEMBL159798 0.79 TXN (0.72) BCHEKMT2AMEN1KDM4EALDH1A1
SCHEMBL10333706 0.78 NPC1 (0.54) BCHEKMT2AMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3980796-A CONTROL OF PARASITES AND NEMATODES HOECHST AKTIENGESELLSCHAFT (DT) 1976-09-14 US claimed
CN-111655677-B Benzimidazole compounds as agrochemicals 瑞戴格作物保护公司 2024-05-03 CN disclosed
EP-3697771-B1 BENZIMIDAZOLE COMPOUNDS AS AGRICULTURAL CHEMICALS REDAG CROP PROT LTD (GB) 2022-04-06 EP disclosed
US-11241013-B2 Benzimidazole compounds as agricultural chemicals REDAG CROP PROT LTD (GB) 2022-02-08 US disclosed
US-20210204547-A1 BENZIMIDAZOLE COMPOUNDS AS AGRICULTURAL CHEMICALS REDAG CROP PROT LTD (GB) 2021-07-08 US disclosed
CN-103736238-B Fire extinguishing composition containing sulfur-containing organic compound 湖北及安盾消防科技有限公司 2020-10-13 CN disclosed
CN-110446950-A structure and optical sensor FUJIFILM CORP 2019-11-12 CN disclosed
CN-109790390-A Dispersion liquid, composition, film, the manufacturing method of film and dispersing agent 富士胶片株式会社 2019-05-21 CN disclosed
CN-106068281-B Colored curable resin composition, cured film, colored filter, the manufacturing method of colored filter, solid-state imaging element, image display device, compound and cation 富士胶片株式会社 2019-04-26 CN disclosed
CN-109073970-A Transfer film, decorative pattern, and touch panel 富士胶片株式会社 2018-12-21 CN disclosed
US-20040259918-A1 Combination therapeutic compositions and method of use TULARIK INC. 2004-12-23 US disclosed
US-6653332-B2 For treatment of diabetes mellitus; for example sulfonamide derivatives of given formula and an antidiabetic agent such as sulfonylureas, biguanides, glitazones, alpha-glucosidase inhibitors, glucagon antagonists TULARIK INC. 2003-11-25 US disclosed
US-20020037928-A1 Combination therapeutic compositions and method of use AMGEN INC. 2002-03-28 US disclosed
WO-2001082916-A2 COMBINATION THERAPEUTIC COMPOSITIONS AND METHODS OF USE TULARIK INC. (US) 2001-11-08 WO disclosed
US-4873346-A BRONCHODILATORS, TREATMENT OF ASTHMA THE UPJOHN COMPANY (US) 1989-10-10 US disclosed
EP-0061446-B1 CHEMICALLY SENSITIZED SILVER HALIDE PHOTOGRAPHIC EMULSIONS AND COLOR PHOTOGRAPHIC ELEMENTS CONTAINING SAID EMULSIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-15 EP disclosed
EP-0061446-A4 CHEMICALLY SENSITIZED SILVER HALIDE PHOTOGRAPHIC EMULSIONS AND COLOR PHOTOGRAPHIC ELEMENTS CONTAINING SAID EMULSIONS. MINNESOTA MINING & MFG (US) 1983-04-18 EP disclosed
EP-0061446-A1 CHEMICALLY SENSITIZED SILVER HALIDE PHOTOGRAPHIC EMULSIONS AND COLOR PHOTOGRAPHIC ELEMENTS CONTAINING SAID EMULSIONS. MINNESOTA MINING & MFG (US) 1982-10-06 EP disclosed
WO-1982001260-A1 CHEMICALLY SENSITIZED SILVER HALIDE PHOTOGRAPHIC EMULSIONS AND COLOR PHOTOGRAPHIC ELEMENTS CONTAINING SAID EMULSIONS MINNESOTA MINING & MFG (US) 1982-04-15 WO disclosed
US-3980796-A CONTROL OF PARASITES AND NEMATODES HOECHST AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020037928-A1 Combination therapeutic compositions and method of use GPR119, GCGR, GLP1R BCHE 2087/4885KMT2A 2525/4885MEN1 4735/4885
US-11241013-B2 Benzimidazole compounds as agricultural chemicals CYP3A4, CYP2C8, CYP2E1 BCHE 41/4885KMT2A 694/4885MEN1 3441/4885
US-20040259918-A1 Combination therapeutic compositions and method of use GPR119, GCGR, GLP1R BCHE 2087/4885KMT2A 2525/4885MEN1 4735/4885
US-20210204547-A1 BENZIMIDAZOLE COMPOUNDS AS AGRICULTURAL CHEMICALS CYP3A4, CYP2C8, CYP2E1 BCHE 41/4885KMT2A 694/4885MEN1 3441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.