Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161073 | 0.82 | HSD11B1 (0.33) | GABRR1 | |
| SCHEMBL25122085 | 0.79 | GABRR1 (0.32) | GABRR1 | |
| SCHEMBL13468803 | 0.77 | TSHR (0.36) | — | |
| SCHEMBL22417755 | 0.76 | GABRR1 (0.31) | GABRR1 | |
| SCHEMBL8490664 | 0.76 | GABRR1 (0.30) | GABRR1 | |
| SCHEMBL22528210 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL20522668 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL13818549 | 0.73 | — | — | |
| SCHEMBL13814962 | 0.73 | HDAC1 (0.31) | — | |
| SCHEMBL13522670 | 0.73 | HTT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2617722-A1 | HETERO RING-FUSED IMIDAZOLE DERIVATIVE HAVING AMPK ACTIVATING EFFECT | Shionogi & Co., Ltd. (JP) | 2013-07-24 | — | — | EP | disclosed |
| WO-2011145035-A1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | INDIAN INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-24 | — | — | WO | disclosed |
| WO-2008067644-A1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-12 | — | — | WO | disclosed |
| US-6008347-A | N-substituted 2-azetidinones | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| US-5412092-A | N-substituted 2-azetidinones | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0627418-A1 | N-subtituted 2-azetidinones and processes for the production of N-unsubstituted 2-azetidinones therefrom | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-12-07 | — | — | EP | disclosed |