Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13493034 | 0.80 | FPR3 (0.30) | — | |
| SCHEMBL8596758 | 0.76 | GPR84 (0.31) | — | |
| SCHEMBL8490658 | 0.76 | GABRR1 (0.34) | GABRR1 | |
| SCHEMBL25122085 | 0.75 | GABRR1 (0.32) | GABRR1 | |
| SCHEMBL21935110 | 0.74 | ALDH1A1 (0.39) | — | |
| SCHEMBL24619779 | 0.73 | — | — | |
| SCHEMBL22417755 | 0.72 | GABRR1 (0.31) | GABRR1 | |
| SCHEMBL25000300 | 0.71 | ALDH1A1 (0.43) | — | |
| SCHEMBL805439 | 0.71 | — | — | |
| SCHEMBL13114290 | 0.69 | GAA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008347-A | N-substituted 2-azetidinones | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| US-5412092-A | N-substituted 2-azetidinones | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0627418-A1 | N-subtituted 2-azetidinones and processes for the production of N-unsubstituted 2-azetidinones therefrom | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-12-07 | — | — | EP | disclosed |