Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493028 | 0.76 | DCTPP1 (0.45) | DCTPP1ALDH1A1L3MBTL1GRM2USP2 | |
| SCHEMBL8486651 | 0.75 | APLNR (0.46) | ALDH1A1KMT2ADRD2 | |
| SCHEMBL11089171 | 0.73 | ALDH1A1 (0.53) | ALDH1A1PKML3MBTL1FGFR1HTT | |
| SCHEMBL14112930 | 0.72 | ALDH1A1 (0.51) | ALDH1A1PKML3MBTL1FGFR1HTT | |
| SCHEMBL993028 | 0.72 | CETP (0.71) | ALDH1A1L3MBTL1HTTGFERCETP | |
| SCHEMBL993229 | 0.72 | CETP (0.71) | ALDH1A1L3MBTL1HTTGFERCETP | |
| SCHEMBL992553 | 0.72 | CETP (0.71) | ALDH1A1L3MBTL1HTTGFERCETP | |
| SCHEMBL993442 | 0.72 | CETP (0.71) | ALDH1A1L3MBTL1HTTGFERCETP | |
| SCHEMBL9796229 | 0.70 | PPARG (0.61) | — | |
| SCHEMBL3297777 | 0.70 | PPARG (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999014204-A1 | SUBSTITUTED 1,2,4-TRIAZOLES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | G.D. SEARLE & CO. (US) | 1999-03-25 | — | — | WO | disclosed |