Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222790 | 1.00 | CA2 (0.73) | CA2ALDH1A1NPSR1CYP3A4CA1 | |
| SCHEMBL1416178 | 1.00 | CA2 (0.73) | CA2ALDH1A1NPSR1CYP3A4CA1 | |
| SCHEMBL2749426 | 0.85 | CA2 (0.59) | CA2ALDH1A1NPSR1CYP3A4CA1 | |
| SCHEMBL18063437 | 0.84 | CA2 (1.00) | CA2ALDH1A1NPSR1CA1CA9 | |
| SCHEMBL18063439 | 0.84 | CA2 (1.00) | CA2ALDH1A1NPSR1CA1CA9 | |
| SCHEMBL17392767 | 0.83 | CA2 (0.56) | CA2ALDH1A1NPSR1CYP3A4KDM4E | |
| SCHEMBL8820316 | 0.83 | CA2 (0.51) | CA2CYP3A4 | |
| SCHEMBL2077365 | 0.83 | CA2 (0.55) | CA2ALDH1A1NPSR1CYP3A4CA1 | |
| SCHEMBL1901250 | 0.83 | CA2 (0.55) | CA2ALDH1A1NPSR1CYP3A4CA1 | |
| SCHEMBL369753 | 0.83 | CA2 (0.55) | CA2ALDH1A1NPSR1CYP3A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312349-B2 | Apoptosis-inducing agents | FOCHON PHARMACEUTICALS, LTD. (CN) | 2025-05-27 | — | — | US | disclosed |
| EP-4119560-B1 | APOPTOSIS-INDUCING AGENTS | FOCHON PHARMACEUTICALS LTD (CN) | 2024-06-05 | — | — | EP | disclosed |
| US-20230159564-A1 | 2-Oxo-Thiazole Derivatives as A2A Inhibitors and Compounds for Use in the Treatment of Cancers | iTeos Belgium SA (BE) | 2023-05-25 | — | — | US | disclosed |
| US-20230159564-A1 | 2-Oxo-Thiazole Derivatives as A2A Inhibitors and Compounds for Use in the Treatment of Cancers | iTeos Belgium SA (BE) | 2023-05-25 | — | — | US | disclosed |
| EP-4119560-A1 | APOPTOSIS-INDUCING AGENTS | Shanghai Fochon Pharmaceutical Co., Ltd. (CN) | 2023-01-18 | — | — | EP | disclosed |
| EP-4112623-A1 | 2-OXO-THIAZOLE DERIVATIVES AS A2A INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS | iTeos Belgium SA (BE) | 2023-01-04 | — | — | EP | disclosed |
| EP-4112623-A1 | 2-OXO-THIAZOLE DERIVATIVES AS A2A INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS | iTeos Belgium SA (BE) | 2023-01-04 | — | — | EP | disclosed |
| US-20220402913-A1 | APOPTOSIS-INDUCING AGENTS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2022-12-22 | — | — | US | disclosed |
| EP-3612531-B1 | APOPTOSIS-INDUCING AGENTS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2022-08-24 | — | — | EP | disclosed |
| EP-3601296-B1 | 2-OXO-THIAZOLE DERIVATIVES AS A2A INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS | iTeos Belgium SA (BE) | 2022-05-25 | — | — | EP | disclosed |
| EP-0249610-B1 | SYNTHESIS OF OPTICALLY ACTIVE ARYLOXYPROPANOLAMINES AND ARYLETHANOLAMINES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-08-25 | — | — | EP | disclosed |
| EP-0322390-B1 | NOVEL ANTIARRHYTHMIC AGENTS I | Aktiebolaget Hässle (SE) | 1992-11-11 | — | — | EP | disclosed |
| US-5155133-A | Antiarrhythmic compounds and pharmaceutical compositions and methods thereof | AKTIEBOLAGET HASSLE (SE) | 1992-10-13 | — | — | US | disclosed |
| US-5010198-A | Intermediates for the synthesis of benzoxazol- and benzothiazolamine derivatives, useful as anti-anoxic agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-23 | — | — | US | disclosed |
| US-4990668-A | Reacting selected dioxolane with hydrohalic acid and organic acid, then with amine | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0184257-B1 | BENZOXAZOL- AND BENZOTHIAZOLAMINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-25 | — | — | EP | disclosed |
| US-4861785-A | Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-08-29 | — | — | US | disclosed |
| WO-1989005794-A1 | NOVEL ANTIARRHYTHMIC AGENTS I | Aktiebolaget Hässle (SE) | 1989-06-29 | — | — | WO | disclosed |
| EP-0322390-A2 | Novel antiarrhythmic agents I | Aktiebolaget Hässle (SE) | 1989-06-28 | — | — | EP | disclosed |
| EP-0184257-A1 | Benzoxazol- and benzothiazolamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402913-A1 | APOPTOSIS-INDUCING AGENTS | BCL2, BAX, BAD | CA2 3261/4885ALDH1A1 3024/4885NPSR1 4768/4885 |
| US-12312349-B2 | Apoptosis-inducing agents | BCL2, BAX, BAD | CA2 3261/4885ALDH1A1 3024/4885NPSR1 4768/4885 |
| US-20230159564-A1 | 2-Oxo-Thiazole Derivatives as A2A Inhibitors and Compounds for Use in the Treatment of Cancers | ADORA2A, ADORA2B, ADORA3 | CA2 793/4885ALDH1A1 123/4885NPSR1 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.