SCHEMBL8493

SCHEMBL8493

[c]1cccc2c1-c1ccccc1-2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPK1 P28482 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CES2 O00748 1/20 0.35
APAF1 O14727 1/20 0.35
TERT O14746 1/20 0.35
NPC1 O15118 1/20 0.35
PLIN1 O60240 1/20 0.35
TDP2 O95551 1/20 0.35
S1PR4 O95977 1/20 0.35
LMNA P02545 1/20 0.35
PLA2G1B P04054 1/20 0.35
BCHE P06276 1/20 0.35
POLB P06746 1/20 0.35
PTPRC P08575 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
PLCG1 P19174 1/20 0.35
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4819516 1.00 MEN1 (0.35) MEN1KMT2AMAPK1KDM4ECES2
SCHEMBL195383 1.00 MEN1 (0.35) MEN1KMT2AMAPK1KDM4ECES2
SCHEMBL14718438 0.85 ALDH1A1 (0.37) MAPK1ALDH1A1TSHRATMHSD17B10
SCHEMBL15062683 0.85
SCHEMBL15062516 0.85
SCHEMBL18844 0.80 S100A4 (0.52) MEN1KMT2AMAPK1KDM4ECES2
SCHEMBL2340183 0.80
SCHEMBL2077973 0.80 MEN1 (0.55) MEN1KMT2AMAPK1KDM4ECES2
SCHEMBL9503298 0.79 MEN1 (0.35) MEN1KMT2AMAPK1KDM4ECES2
SCHEMBL12816458 0.79 NOTUM (0.34) MEN1KMT2AMAPK1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9893 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112384595-B Material for organic electroluminescent device 默克专利有限公司 2024-05-28 CN claimed
CN-117917206-A Organic light emitting diode and compound used therein 诺瓦尔德股份有限公司 2024-04-19 CN claimed
CN-112469690-B Method for producing arylamines 默克专利有限公司 2024-04-16 CN claimed
US-11952460-B2 Polycarbonate resin, method for producing the same, and optical lens MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-04-09 US claimed
WO-2024037851-A1 USE OF ADDITIVES FOR IMPROVING THE PROCESSING OF POLYETHYLENES BASF SE (DE) 2024-02-22 WO claimed
US-11903311-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-02-13 US claimed
US-11849634-B2 Composition of matter for use in organic light- emitting diodes KYULUX, INC. (JP) 2023-12-19 US claimed
US-20230391704-A1 TRIARYLMETHANE COMPOUNDS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-07 US claimed
US-11771088-B2 Insecticidal compositions and methods MONSANTO TECHNOLOGY LLC (US) 2023-10-03 US claimed
CN-111094297-B Organic compound, composition, organic electro-optical device, and display device 三星SDI株式会社 2023-07-18 CN claimed
US-4997836-A Inhibitor of platelet activating factor TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-03-05 US claimed
US-4880809-A HYPOTENSIVE AGENTS, AMIDE DERIVATIVES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-11-14 US claimed
US-4756989-A Aluminum or silicon substrate, copolymer resist layer comprising vinyl aromatic, ethylenically unsaturated units ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US claimed
US-4140681-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1979-02-20 US claimed
US-4131673-A INHIBITION AND SUPPRESSION OF THROMBOSIS IN MAMMALS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1978-12-26 US claimed
US-4125604-A PEPTIDES, ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-11-14 US claimed
US-4101653-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-18 US claimed
US-4097472-A INHIBITION AND SUPRESSION OF THROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-27 US claimed
US-4093712-A ANTITHROMBOGENIC AGENTS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-06 US claimed
US-4066773-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1978-01-03 US claimed