Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493 | 0.79 | MEN1 (0.35) | MEN1KMT2ACDC25BALDH1A1NPC1 | |
| SCHEMBL4819516 | 0.79 | MEN1 (0.35) | MEN1KMT2ACDC25BALDH1A1NPC1 | |
| SCHEMBL195383 | 0.79 | MEN1 (0.35) | MEN1KMT2ACDC25BALDH1A1NPC1 | |
| SCHEMBL646330 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KDM4E | |
| SCHEMBL56824 | 0.77 | CDC25B (0.55) | MEN1KMT2ACDC25BALDH1A1NPC1 | |
| SCHEMBL2407852 | 0.75 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL2407346 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPK1L3MBTL1KDM4ECES2 | |
| SCHEMBL15062683 | 0.73 | — | — | |
| SCHEMBL15062516 | 0.73 | — | — | |
| SCHEMBL10337930 | 0.72 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364892-B1 | WHOLLY AROMATIC POLYAMIDES, PROCESS FOR PRODUCING THE SAME AND SHAPED ARTICLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-09 | — | — | EP | claimed |
| EP-0364891-B1 | WHOLLY AROMATIC POLYAMIDES, PROCESS FOR PRODUCING THE SAME AND SHAPED ARTICLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-09 | — | — | EP | claimed |
| US-10472381-B2 | Sialic acid derivatives | REINHARD BROSSMER (DE) | 2019-11-12 | — | — | US | disclosed |
| WO-2018172129-A1 | SIALIC ACID DERIVATIVES WITH C-C TRIPLE BOND, AND PREPARATION THEREOF | PRESCHER HORST (CH) | 2018-09-27 | — | — | WO | disclosed |
| EP-3129390-A1 | SIALIC ACID DERIVATIVES | Brossmer, Reinhard (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-20160362436-A1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2016-12-15 | — | — | US | disclosed |
| EP-2797946-B1 | SIALIC ACID DIMERS | BROSSMER REINHARD (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-9260467-B2 | Sialic acid dimers | BROSSMER REINHARD (DE) | 2016-02-16 | — | — | US | disclosed |
| WO-2015128344-A1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2015-09-03 | — | — | WO | disclosed |
| EP-2910561-A1 | Sialic acid derivatives | Brossmer, Reinhard (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-20150005245-A1 | Sialic Acid Dimers | BROSSMER REINHARD (DE) | 2015-01-01 | — | — | US | disclosed |
| EP-2797946-A1 | SIALIC ACID DIMERS | Brossmer, Reinhard (DE) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013097942-A1 | SIALIC ACID DIMERS | BROSSMER REINHARD (DE) | 2013-07-04 | — | — | WO | disclosed |
| EP-2610263-A1 | Sialic acid dimers | Brossmer, Reinhard (DE) | 2013-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10472381-B2 | Sialic acid derivatives | NEU1, NEU2, NEU3 | MEN1 1137/4885KMT2A 4412/4885CDC25B 3997/4885 |
| US-20160362436-A1 | SIALIC ACID DERIVATIVES | NEU1, NEU2, NEU3 | MEN1 1135/4885KMT2A 4414/4885CDC25B 3994/4885 |
| US-20150005245-A1 | Sialic Acid Dimers | SIGLEC9, SIGLEC7, NEU2 | MEN1 2389/4885KMT2A 3967/4885CDC25B 2651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.