Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | QPCT | Q16769 | 2/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14242734 | 0.87 | AKR1B1 (0.53) | ALOX15AKR1B1ALDH1A1MAOBCYP3A4 | |
| SCHEMBL7574697 | 0.87 | ALOX15 (0.66) | ALOX15ALDH1A1MAOBCYP3A4HPGD | |
| SCHEMBL7372279 | 0.83 | EPHX2 (0.61) | ALOX15AKR1B1ALDH1A1MAOBCYP3A4 | |
| SCHEMBL25412346 | 0.80 | ALOX15 (0.57) | ALOX15AKR1B1ALDH1A1HPGDKDM4E | |
| SCHEMBL3844782 | 0.78 | ALOX15 (0.54) | ALOX15ALDH1A1CYP3A4HPGDKDM4E | |
| SCHEMBL29379868 | 0.77 | HSD17B3 (0.61) | ALOX15AKR1B1ALDH1A1MAOBCYP3A4 | |
| SCHEMBL1500217 | 0.77 | HSD17B3 (0.61) | ALOX15AKR1B1ALDH1A1MAOBCYP3A4 | |
| SCHEMBL12867892 | 0.77 | ALOX15 (0.57) | ALOX15ALDH1A1MAOBCYP3A4HPGD | |
| SCHEMBL8782604 | 0.76 | HPGD (0.60) | ALOX15AKR1B1ALDH1A1MAOBCYP3A4 | |
| SCHEMBL22703864 | 0.75 | HSD17B3 (0.51) | AKR1B1ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977351-A | Benzpyrylium squarylium and croconylium dyes, and processes for their preparation and use | POLAROID CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5627014-A | COMPOSITIONS FOR ABSORBERS OF HEAT WHILE COLORING | POLAROID CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0511381-B1 | SQUARYLIUM AND CROCONYLIUM DYES | POLAROID CORP (US) | 1995-07-26 | — | — | EP | disclosed |
| US-5405976-A | Infrared absorbers; solubility in solvents, polymers | POLAROID CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |
| EP-0511381-A1 | SQUARYLIUM AND CROCONYLIUM DYES. | POLAROID CORP (US) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992009661-A1 | SQUARYLIUM AND CROCONYLIUM DYES | POLAROID CORPORATION (US) | 1992-06-11 | — | — | WO | disclosed |