Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493141 | 0.84 | ALDH1A1 (0.56) | ALOX15EPHX2ALDH1A1KDM4EIGLV6-57 | |
| SCHEMBL25411899 | 0.82 | ALOX15 (0.46) | ALOX15QPCTEPHX2STSALDH1A1 | |
| SCHEMBL25413865 | 0.79 | IGLV6-57 (0.60) | ALOX15QPCTEPHX2STSALDH1A1 | |
| SCHEMBL25412346 | 0.78 | ALOX15 (0.57) | ALOX15EPHX2STSALDH1A1KDM4E | |
| SCHEMBL8493156 | 0.78 | ALOX15 (0.66) | ALOX15QPCTTNKSALDH1A1KDM4E | |
| SCHEMBL22032720 | 0.75 | QPCT (0.79) | QPCTTNKSALDH1A1KDM4EAPP | |
| SCHEMBL12867892 | 0.75 | ALOX15 (0.57) | ALOX15TNKSSTSALDH1A1KDM4E | |
| SCHEMBL840516 | 0.74 | KDM4E (0.48) | QPCTTNKSALDH1A1CCR4KDM4E | |
| SCHEMBL30352933 | 0.74 | KDM4E (0.48) | QPCTTNKSALDH1A1CCR4KDM4E | |
| SCHEMBL23172755 | 0.73 | APP (0.43) | ALOX15ALDH1A1APPSLC16A3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210363124-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-11-25 | — | — | US | disclosed |
| WO-2020118116-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-06-11 | — | — | WO | disclosed |
| US-20090252687-A1 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | COOPER MICHAEL EDWARD | 2009-10-08 | — | — | US | disclosed |
| EP-2046895-A2 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | GE Healthcare AS (NO) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008015415-A2 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | GE HEALTHCARE AS (NO) | 2008-02-07 | — | — | WO | disclosed |
| US-5977351-A | Benzpyrylium squarylium and croconylium dyes, and processes for their preparation and use | POLAROID CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5627014-A | COMPOSITIONS FOR ABSORBERS OF HEAT WHILE COLORING | POLAROID CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| US-5405976-A | Infrared absorbers; solubility in solvents, polymers | POLAROID CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |
| US-5262549-A | Visible and near infra-red absorbers for images | POLAROID CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090252687-A1 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | FCGR2A, FCGR3B, FCER2 | ALOX15 3667/4885QPCT 123/4885EPHX2 746/4885 |
| US-20210363124-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | SMARCE1, CRY2, WDR82 | ALOX15 3731/4885QPCT 971/4885EPHX2 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.