SCHEMBL8493545

SCHEMBL8493545

Cc1cc(S(=O)(=O)c2ccc(O)cc2)ccc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.60
PKM P14618 2/20 0.60
ALDH1A1 P00352 2/20 0.60
RAPGEF4 Q8WZA2 1/20 0.58
MAPT P10636 2/20 0.50
CA2 P00918 3/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA9 Q16790 1/20 0.47
ENPP2 Q13822 1/20 0.47
POLB P06746 3/20 0.46
ESR1 P03372 2/20 0.45
BACE1 P56817 1/20 0.45
ELANE P08246 1/20 0.45
ESR2 Q92731 1/20 0.44
GFER P55789 1/20 0.44
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8908176 1.00 GAA (0.60) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL29599083 0.92 GAA (0.58) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL69907 0.92 GAA (0.58) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL12460963 0.89 GAA (0.61) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL9460744 0.87 POLB (0.59) GAAPKMALDH1A1MAPTPOLB
SCHEMBL5146968 0.86 ALDH1A1 (0.67) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL12084146 0.86 ALDH1A1 (0.67) GAAPKMALDH1A1MAPTPOLB
SCHEMBL14855745 0.82 GAA (0.67) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL8494504 0.82 PKM (0.64) GAAPKMALDH1A1RAPGEF4CA2
SCHEMBL34461892 0.82 SERPINE1 (0.55) GAAPKMALDH1A1RAPGEF4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3461856-A1 COMPOSITION FOR PREPARING POLY(IMIDE-AMIDE)COPOLYMER, POLY(IMIDE-AMIDE)COPOLYMER, ARTICLE CONTAINING POLY(IMIDE-AMIDE)COPOLYMER, AND ELECTRONIC DEVICE INCLUDING SAME Samsung Electronics Co., Ltd. (KR) 2019-04-03 EP disclosed
US-10197914-B2 Positive photosensitive resin composition, photo-curable dry film and method for producing the same, patterning process, and laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-02-05 US disclosed
US-20170255097-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PHOTO-CURABLE DRY FILM AND METHOD FOR PRODUCING THE SAME, PATTERNING PROCESS, AND LAMINATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-09-07 US disclosed
EP-3156436-A1 POLY(IMIDE-AMIDE)COPOLYMER, METHOD FOR PREPARING POLY(IMIDE-AMIDE)COPOLYMER, ARTICLE CONTAINING POLY(IMIDE-AMIDE)COPOLYMER, AND ELECTRONIC DEVICE INCLUDING SAME Samsung Electronics Co., Ltd. (KR) 2017-04-19 EP disclosed
EP-0697291-B1 4-HYDROXY-4'-ISOPROPOXYDIPHENYL SULFONE DEVELOPER COMPOSITION, WET PULVERIZING METHOD, AND DISPERSION NIPPON SODA CO (JP) 1999-06-16 EP disclosed
US-5609672-A Composition for color development comprising 4-hydroxy-4'-isopropoxydiphenylsulfone, and a wet method for grinding and a dispersible solution for applying the same NIPPON SODA CO., LTD. (JP) 1997-03-11 US disclosed
EP-0697291-A1 4-HYDROXY-4'-ISOPROPOXYDIPHENYL SULFONE DEVELOPER COMPOSITION, WET PULVERIZING METHOD, AND DISPERSION NIPPON SODA CO., LTD. (JP) 1996-02-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10197914-B2 Positive photosensitive resin composition, photo-curable dry film and method for producing the same, patterning process, and laminate SUV39H1, JMJD6, EZH1 GAA 2543/4885PKM 3277/4885ALDH1A1 1140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.