SCHEMBL8908176

SCHEMBL8908176

Cc1cc(S(=O)(=O)c2ccc(O)c(C)c2)ccc1O.O=S(=O)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.60
PKM P14618 2/20 0.60
ALDH1A1 P00352 2/20 0.60
RAPGEF4 Q8WZA2 1/20 0.58
MAPT P10636 2/20 0.50
CA2 P00918 3/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA9 Q16790 1/20 0.47
ENPP2 Q13822 1/20 0.47
POLB P06746 3/20 0.46
ESR1 P03372 2/20 0.45
BACE1 P56817 1/20 0.45
ELANE P08246 1/20 0.45
ESR2 Q92731 1/20 0.44
GFER P55789 1/20 0.44
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8493545 1.00 GAA (0.60) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL29599083 0.92 GAA (0.58) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL69907 0.92 GAA (0.58) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL12460963 0.89 GAA (0.61) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL9460744 0.87 POLB (0.59) GAAPKMALDH1A1MAPTPOLB
SCHEMBL5146968 0.86 ALDH1A1 (0.67) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL12084146 0.86 ALDH1A1 (0.67) GAAPKMALDH1A1MAPTPOLB
SCHEMBL14855745 0.82 GAA (0.67) GAAPKMALDH1A1RAPGEF4MAPT
SCHEMBL8494504 0.82 PKM (0.64) GAAPKMALDH1A1RAPGEF4CA2
SCHEMBL34461892 0.82 SERPINE1 (0.55) GAAPKMALDH1A1RAPGEF4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11414523-B2 Polycarbonate-polydiorganosiloxane copolymer, resin composition of polycarbonate-polydiorganosiloxane copolymer, and production method for resin composition of polycarbonate-polydiorganosiloxane copolymer TEIJIN LIMITED (JP) 2022-08-16 US disclosed
US-20210108033-A1 POLYCARBONATE-POLYDIORGANOSILOXANE COPOLYMER, RESIN COMPOSITION OF POLYCARBONATE-POLYDIORGANOSILOXANE COPOLYMER, AND PRODUCTION METHOD FOR RESIN COMPOSITION OF POLYCARBONATE-POLYDIORGANOSILOXANE COPOLYMER TEIJIN LIMITED (JP) 2021-04-15 US disclosed
US-RE35499-E MOLDED ARTICLES SUCH AS COMPACT DISKS THE DOW CHEMICAL COMPANY (US) 1997-04-29 US disclosed