SCHEMBL849374

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13552082	0.98	TAAR1 (0.50)	TAAR1GPR52CA1CA2CA12
	SCHEMBL28000111	0.82	TAAR1 (0.54)	TAAR1GPR52CA1CA2CA12
	SCHEMBL9775042	0.80	TAAR1 (0.42)	TAAR1CA1CA2CA12CA9
	SCHEMBL31627087	0.78	TAAR1 (0.50)	TAAR1GPR52CA1CA2CA12
	SCHEMBL848881	0.78	TAAR1 (0.50)	TAAR1GPR52CA1CA2CA12
	SCHEMBL13555094	0.78	TAAR1 (0.50)	TAAR1GPR52CA1CA2CA12
	SCHEMBL9300506	0.78	TAAR1 (0.43)	TAAR1CA1CA2CA12CA9
	SCHEMBL849373	0.77	TAAR1 (0.48)	TAAR1GPR52CA1CA2CA12
	SCHEMBL10976350	0.76	MGLL (0.56)	TAAR1CA1CA2CA12CA9
	SCHEMBL4967989	0.75	PKM (0.34)	CA1CA2CA12CA9L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.