Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 5/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494140 | 1.00 | G6PC1 (0.64) | G6PC1ATMALDH1A1TSHRCA12 | |
| SCHEMBL8498152 | 0.91 | G6PC1 (0.54) | G6PC1ATMALDH1A1TSHRCA12 | |
| SCHEMBL8496840 | 0.90 | G6PC1 (0.53) | G6PC1ATMALDH1A1TSHRCA12 | |
| SCHEMBL8496844 | 0.90 | G6PC1 (0.53) | G6PC1ATMALDH1A1TSHRCA12 | |
| SCHEMBL8498588 | 0.89 | G6PC1 (0.51) | G6PC1ATMTP53MAPTMEN1 | |
| SCHEMBL8498591 | 0.89 | G6PC1 (0.51) | G6PC1ATMTP53MAPTMEN1 | |
| SCHEMBL8498364 | 0.86 | G6PC1 (0.52) | G6PC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8498363 | 0.86 | G6PC1 (0.52) | G6PC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15439323 | 0.84 | G6PC1 (0.54) | G6PC1ATMALDH1A1CA12CA9 | |
| SCHEMBL15439321 | 0.84 | G6PC1 (0.54) | G6PC1ATMALDH1A1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |