Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498588 | 1.00 | G6PC1 (0.51) | G6PC1ATMTMEM97SIGMAR1AGER | |
| SCHEMBL8494140 | 0.89 | G6PC1 (0.64) | G6PC1ATMMAPTMEN1KMT2A | |
| SCHEMBL8494142 | 0.89 | G6PC1 (0.64) | G6PC1ATMMAPTMEN1KMT2A | |
| SCHEMBL8496844 | 0.86 | G6PC1 (0.53) | G6PC1ATMMAPTL3MBTL1TAS2R14 | |
| SCHEMBL8496840 | 0.86 | G6PC1 (0.53) | G6PC1ATMMAPTL3MBTL1TAS2R14 | |
| SCHEMBL8498363 | 0.82 | G6PC1 (0.52) | G6PC1SIGMAR1L3MBTL1TAS2R14MEN1 | |
| SCHEMBL8498364 | 0.82 | G6PC1 (0.52) | G6PC1SIGMAR1L3MBTL1TAS2R14MEN1 | |
| SCHEMBL8498741 | 0.82 | MEN1 (0.41) | G6PC1ATMTMEM97SIGMAR1AGER | |
| SCHEMBL8498152 | 0.81 | G6PC1 (0.54) | G6PC1ATMMAPTL3MBTL1MEN1 | |
| SCHEMBL8497057 | 0.80 | GAA (0.43) | G6PC1ATMTMEM97SIGMAR1AGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |