Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498364 | 1.00 | G6PC1 (0.52) | G6PC1ACHEMEN1ALDH1A1ALOX12 | |
| SCHEMBL8495082 | 0.92 | G6PC1 (0.46) | G6PC1ACHEMEN1ALDH1A1ALOX12 | |
| SCHEMBL8495078 | 0.92 | G6PC1 (0.46) | G6PC1ACHEMEN1ALDH1A1ALOX12 | |
| SCHEMBL8494140 | 0.86 | G6PC1 (0.64) | G6PC1MEN1ALDH1A1KMT2ARAB9A | |
| SCHEMBL8494142 | 0.86 | G6PC1 (0.64) | G6PC1MEN1ALDH1A1KMT2ARAB9A | |
| SCHEMBL8497170 | 0.85 | ACHE (0.48) | G6PC1ACHEMEN1ALDH1A1ALOX12 | |
| SCHEMBL8497173 | 0.85 | ACHE (0.48) | G6PC1ACHEMEN1ALDH1A1ALOX12 | |
| SCHEMBL8496840 | 0.84 | G6PC1 (0.53) | G6PC1ACHEMEN1ALDH1A1KMT2A | |
| SCHEMBL8496844 | 0.84 | G6PC1 (0.53) | G6PC1ACHEMEN1ALDH1A1KMT2A | |
| SCHEMBL8498588 | 0.82 | G6PC1 (0.51) | G6PC1MEN1KMT2AL3MBTL1TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | claimed |