Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800406 | 1.00 | POLB (0.50) | POLBDDB1CRBNMEN1KMT2A | |
| SCHEMBL8495437 | 0.92 | ATM (0.51) | DDB1CRBNMEN1KMT2AALDH1A1 | |
| SCHEMBL8495439 | 0.92 | ATM (0.51) | DDB1CRBNMEN1KMT2AALDH1A1 | |
| SCHEMBL10691676 | 0.84 | HTR2C (0.60) | DDB1CRBNMEN1KMT2AALDH1A1 | |
| SCHEMBL14140969 | 0.79 | POLB (0.53) | POLBALDH1A1HSD11B1NPC1PKM | |
| SCHEMBL14140972 | 0.79 | POLB (0.53) | POLBALDH1A1HSD11B1NPC1PKM | |
| SCHEMBL7351360 | 0.78 | HTR2C (0.56) | MEN1KMT2AALDH1A1HSD11B1HTR2C | |
| SCHEMBL28950554 | 0.78 | POLB (0.51) | POLBALDH1A1HSD11B1NPC1PKM | |
| SCHEMBL28950551 | 0.78 | POLB (0.51) | POLBALDH1A1HSD11B1NPC1PKM | |
| SCHEMBL28439668 | 0.78 | POLB (0.51) | POLBHSD11B1SMN1; SMN2NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720599-B1 | HYDROXY-SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORP (US) | 1999-05-19 | — | — | EP | claimed |