Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.42 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28950551 | 1.00 | POLB (0.51) | POLBNPC1PKMRAB9AMGLL | |
| SCHEMBL14301511 | 0.83 | ROCK2 (0.47) | POLBNPC1PKMRAB9AMGLL | |
| SCHEMBL10735543 | 0.83 | ALDH1A1 (0.45) | POLBGRM2LMNAGAAALDH1A1 | |
| SCHEMBL10735537 | 0.83 | ALDH1A1 (0.45) | POLBGRM2LMNAGAAALDH1A1 | |
| SCHEMBL14140969 | 0.81 | POLB (0.53) | POLBNPC1PKMRAB9AMGLL | |
| SCHEMBL14140972 | 0.81 | POLB (0.53) | POLBNPC1PKMRAB9AMGLL | |
| SCHEMBL30777491 | 0.80 | TP53 (0.47) | NPC1PKMRAB9AMGLLGRM2 | |
| SCHEMBL28439668 | 0.79 | POLB (0.51) | POLBNPC1PKMRAB9AMGLL | |
| SCHEMBL11376519 | 0.79 | NR4A2 (0.46) | POLBNPC1PKMRAB9AGRM2 | |
| SCHEMBL8494181 | 0.78 | POLB (0.50) | POLBNPC1PKMRAB9AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957385-B | Dipeptide compound containing beta-lactam ring, preparation method and application thereof | 浙大城市学院 | 2024-02-27 | — | — | CN | disclosed |
| CN-114957385-A | Dipeptide compound containing beta-lactam ring, preparation method and application thereof | 浙大城市学院 | 2022-08-30 | — | — | CN | disclosed |