Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495439 | 1.00 | ATM (0.51) | ATMGRM2THRBCTSGCMA1 | |
| SCHEMBL8494181 | 0.92 | POLB (0.50) | ATMGRM2DDB1CRBNALDH1A1 | |
| SCHEMBL2800406 | 0.92 | POLB (0.50) | ATMGRM2DDB1CRBNALDH1A1 | |
| SCHEMBL225262 | 0.84 | KMT2A (0.47) | GRM2DDB1CRBNALDH1A1MAPT | |
| Water SCHEMBL2910884 | 0.82 | KMT2A (0.45) | GRM2DDB1CRBNALDH1A1MAPT | |
| SCHEMBL10691676 | 0.77 | HTR2C (0.60) | DDB1CRBNALDH1A1MAPTKMT2A | |
| SCHEMBL6964905 | 0.73 | FADS1 (0.50) | CTSGCMA1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL6312665 | 0.73 | MAPT (0.56) | ATMTHRBALDH1A1MAPTKMT2A | |
| SCHEMBL14140969 | 0.72 | POLB (0.53) | GRM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL14140972 | 0.72 | POLB (0.53) | GRM2ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720599-B1 | HYDROXY-SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORP (US) | 1999-05-19 | — | — | EP | claimed |