SCHEMBL8494362

SCHEMBL8494362

OC[C@H]1O[C@@H](n2c(O)nc3c(O)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.61
HSPA8 P11142 2/20 0.61
RXFP1 Q9HBX9 1/20 0.56
GAPDH P04406 2/20 0.54
HSD17B10 Q99714 1/20 0.54
LMNA P02545 1/20 0.53
TP53 P04637 1/20 0.53
HBB P68871 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ADK P55263 3/20 0.52
DPP4 P27487 1/20 0.50
CDK5 Q00535 1/20 0.50
CDK5R1 Q15078 1/20 0.50
ADORA3 P0DMS8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8494383 1.00 HSPA5 (0.61) HSPA5HSPA8RXFP1GAPDHHSD17B10
SCHEMBL18952787 0.89 ADK (0.65) HSPA5HSPA8RXFP1GAPDHHSD17B10
SCHEMBL18952790 0.89 ADK (0.65) HSPA5HSPA8RXFP1GAPDHHSD17B10
SCHEMBL6305168 0.88 HSPA8 (0.80) HSPA5HSPA8RXFP1GAPDHHSD17B10
SCHEMBL5362344 0.88 HSPA8 (0.80) HSPA5HSPA8RXFP1GAPDHHSD17B10
SCHEMBL23498581 0.88 HSPA8 (0.59) HSPA5HSPA8RXFP1GAPDHHSD17B10
SCHEMBL1144664 0.88 NADK (0.60) HSPA5HSPA8RXFP1GAPDHHSD17B10
SCHEMBL6434241 0.88 HSPA8 (0.80) HSPA5HSPA8RXFP1GAPDHHSD17B10
SCHEMBL1144665 0.88 NADK (0.60) HSPA5HSPA8RXFP1GAPDHHSD17B10
SCHEMBL1144992 0.88 ADK (0.66) HSPA5HSPA8RXFP1GAPDHHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US disclosed
WO-1999050447-A1 METHOD AND NUCLEIC ACID COMPOUND FOR BREAKING DOWN NUCLEIC ACID MOLECULES SYNTHESIZED $i(IN VITRO) MIRA DIAGNOSTIKA GMBH (DE) 1999-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 HSPA5 393/4885HSPA8 819/4885RXFP1 3003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.