Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.60 |
| ▸ | DGKA | P23743 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1828752 | 0.94 | HTR2C (0.64) | NAAADGKAHTR2CRAD52NPSR1 | |
| Sulfuric Acid SCHEMBL22031604 | 0.93 | DGKA (0.71) | NAAADGKAHTR2CRAD52NPSR1 | |
| Sulfuric Acid SCHEMBL11047305 | 0.92 | HTR2C (0.66) | NAAADGKAHTR2CRAD52NPSR1 | |
| Sulfuric Acid SCHEMBL27969861 | 0.91 | HTR2C (0.60) | NAAADGKAHTR2CRAD52NPSR1 | |
| Sulfuric Acid SCHEMBL7793923 | 0.91 | DGKA (0.69) | NAAADGKAHTR2CRAD52NPSR1 | |
| Sulfuric Acid SCHEMBL11347430 | 0.91 | DGKA (0.74) | NAAADGKAHTR2CRAD52NPSR1 | |
| Sulfuric Acid SCHEMBL9841068 | 0.91 | DGKA (0.74) | NAAADGKAHTR2CRAD52NPSR1 | |
| SCHEMBL1171560 | 0.90 | NAAA (0.72) | NAAADGKAHTR2CRAD52NPSR1 | |
| SCHEMBL2891994 | 0.90 | NAAA (0.72) | NAAADGKAHTR2CRAD52NPSR1 | |
| SCHEMBL128168 | 0.90 | NAAA (0.72) | NAAADGKAHTR2CRAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965500-A | HIGH FOAMING AQUEOUS LIQUID CLEANSER WITH LEVELS OF OIL/EMOLLIENT EQUAL TO OR IN EXCESS OF LEVEL OF SURFACTANT; SHOWER GELS AND CLEANSERS | LEVERS BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1999-10-12 | — | — | US | disclosed |