Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 5/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495993 | 0.84 | NFE2L2 (0.50) | FFAR4 | |
| SCHEMBL8496114 | 0.83 | NFE2L2 (0.52) | FFAR4 | |
| SCHEMBL3067622 | 0.79 | PARP15 (0.54) | PARP15PARP10PARP2 | |
| SCHEMBL8494092 | 0.76 | HPGD (0.45) | FFAR4 | |
| SCHEMBL3651563 | 0.76 | HTR2C (0.47) | PARP15PARP10PARP2 | |
| SCHEMBL8884937 | 0.74 | PARP10 (0.58) | PARP15PARP10PARP2MAOBMAOA | |
| SCHEMBL8496390 | 0.74 | LTA4H (0.53) | FFAR4 | |
| SCHEMBL6539202 | 0.73 | MCHR1 (0.44) | PARP15PARP10 | |
| SCHEMBL23483166 | 0.72 | LTA4H (0.56) | PARP15PARP10PARP2MAOBMAOA | |
| SCHEMBL8882858 | 0.72 | PARP10 (0.59) | PARP15PARP10PARP2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932543-A | INHIBITING FUNGAL AND PARASITIC ACTIVITY | ELI LILLY AND COMPANY (US) | 1999-08-03 | — | — | US | disclosed |