Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 8/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496114 | 0.99 | NFE2L2 (0.52) | NFE2L2HPGDTGFBR1HCRTR1HCRTR2 | |
| SCHEMBL8495284 | 0.84 | PARP15 (0.47) | FFAR4 | |
| SCHEMBL8494092 | 0.82 | HPGD (0.45) | HPGDHCRTR1HCRTR2FFAR4ALDH1A1 | |
| SCHEMBL3079539 | 0.80 | NFE2L2 (0.58) | NFE2L2HPGDGRM2ALDH1A1 | |
| SCHEMBL3072287 | 0.79 | NFE2L2 (0.60) | NFE2L2HPGDTGFBR1GRM2 | |
| SCHEMBL8883764 | 0.77 | IDO1 (0.48) | NFE2L2HPGDIDO1C5AR1 | |
| SCHEMBL8496390 | 0.77 | LTA4H (0.53) | HPGDFFAR4ALDH1A1 | |
| SCHEMBL8491685 | 0.77 | PPARA (0.40) | HPGDIDO1FFAR4ALDH1A1 | |
| SCHEMBL8883838 | 0.76 | IDO1 (0.49) | NFE2L2HPGDIDO1C5AR1 | |
| SCHEMBL8492656 | 0.74 | LTA4H (0.54) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932543-A | INHIBITING FUNGAL AND PARASITIC ACTIVITY | ELI LILLY AND COMPANY (US) | 1999-08-03 | — | — | US | disclosed |