SCHEMBL8495405

SCHEMBL8495405

NNC(=O)CCCCC(N)C(=O)NN

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.42
CTSD P07339 1/20 0.40
KDM4E B2RXH2 1/20 0.40
KDM5C P41229 1/20 0.40
PHF8 Q9UPP1 1/20 0.40
KDM2A Q9Y2K7 1/20 0.40
DPP7 Q9UHL4 3/20 0.38
SLC15A1 P46059 1/20 0.38
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
GSR P00390 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM1 P11229 1/20 0.36
NOD1 Q9Y239 1/20 0.36
ENPEP Q07075 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28845044 0.94 CTSD (0.41) ALDH1A1GAACTSDKDM4EKDM5C
SCHEMBL1534035 0.85 CTSD (0.44) ALDH1A1GAACTSDKDM4EKDM5C
SCHEMBL308629 0.85 CTSD (0.44) ALDH1A1GAACTSDKDM4EKDM5C
SCHEMBL1534041 0.85 CTSD (0.44) ALDH1A1GAACTSDKDM4EKDM5C
SCHEMBL6315105 0.79 GSR (0.59) DPP7GNAI3GNAO1GNAI1GSR
SCHEMBL6315100 0.79 GSR (0.59) DPP7GNAI3GNAO1GNAI1GSR
SCHEMBL5859694 0.78 CA1 (0.47) ALDH1A1GAACTSDKDM4EKDM5C
SCHEMBL17131125 0.78 DPP7 (0.61) DPP7SLC15A1GNAI3GNAO1GNAI1
SCHEMBL49856 0.78 ALDH1A1 (0.62) ALDH1A1GAACTSDKDM4EKDM5C
SCHEMBL28219205 0.78 ALDH1A1 (0.62) ALDH1A1GAACTSDKDM4EKDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5874417-A A CROSSLINKED COMPOSITION HAVING CONJUGATED SITE AT GLUCURONIC ACID WITH A MONO HYDRAZIDE OR A POLYHYDRAZIDE AND A PLURALITY OF CELLS FOR TISSUE ENGINEERING, A COSMETIC AGENT, AND A DRUG; DRUG DELIVERY THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1999-02-23 US claimed