Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327234 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1MAPK1KCNH2 | |
| Hydrochloric Acid SCHEMBL9532204 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1MAPK1KCNH2 | |
| SCHEMBL10770556 | 0.78 | MEN1 (0.47) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL7321621 | 0.78 | KDM4E (0.59) | ALDH1A1KMT2AMEN1KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL9528868 | 0.77 | KDM4E (0.57) | ALDH1A1KMT2AMEN1KCNH2HRH3 | |
| SCHEMBL8495200 | 0.77 | IDO1 (0.44) | ALDH1A1KMT2AMEN1MAPK1HRH3 | |
| SCHEMBL8498206 | 0.77 | KDM4E (0.60) | ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9529314 | 0.76 | KCNH2 (0.58) | ALDH1A1KMT2AMEN1KCNH2HRH3 | |
| SCHEMBL7322566 | 0.75 | TMEM97 (0.61) | KCNH2HRH3 | |
| SCHEMBL3078119 | 0.74 | HRH3 (0.51) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932543-A | INHIBITING FUNGAL AND PARASITIC ACTIVITY | ELI LILLY AND COMPANY (US) | 1999-08-03 | — | — | US | disclosed |