Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 3/20 | 0.36 |
| ▸ | FABP4 | P15090 | 3/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883838 | 0.78 | IDO1 (0.49) | IDO1KDM4EC5AR1MCHR1 | |
| SCHEMBL8496348 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL8883764 | 0.76 | IDO1 (0.48) | IDO1KDM4EC5AR1MCHR1 | |
| SCHEMBL8492834 | 0.75 | KDM4E (0.51) | ALDH1A1TSHRHTTKDM4ESMN1; SMN2 | |
| SCHEMBL3085582 | 0.72 | NFE2L2 (0.47) | HRH3 | |
| SCHEMBL8496114 | 0.72 | NFE2L2 (0.52) | IDO1C5AR1HRH3 | |
| SCHEMBL8498206 | 0.71 | KDM4E (0.60) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8495993 | 0.70 | NFE2L2 (0.50) | IDO1ALDH1A1C5AR1LMNA | |
| SCHEMBL10770556 | 0.66 | MEN1 (0.47) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9411215 | 0.65 | ACHE (0.51) | ALDH1A1SLC18A3TP53HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932543-A | INHIBITING FUNGAL AND PARASITIC ACTIVITY | ELI LILLY AND COMPANY (US) | 1999-08-03 | — | — | US | disclosed |