Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tromethamine SCHEMBL11022757 | 0.81 | TAAR1 (0.47) | TAAR1TRPA1AOC3RIPK1KDM4E | |
| SCHEMBL15958712 | 0.78 | AOC3 (0.47) | AOC3RIPK1KDM4EPOLBLMNA | |
| SCHEMBL20342289 | 0.78 | TRPA1 (0.50) | TAAR1TRPA1AOC3RIPK1KDM4E | |
| SCHEMBL18567132 | 0.78 | TRPA1 (0.50) | TAAR1TRPA1AOC3RIPK1KDM4E | |
| SCHEMBL21322418 | 0.78 | TAAR1 (0.56) | TAAR1TRPA1AOC3RIPK1KDM4E | |
| SCHEMBL21688445 | 0.76 | TAAR1 (0.54) | TAAR1TRPA1AOC3RIPK1KDM4E | |
| SCHEMBL38652448 | 0.76 | TAAR1 (0.53) | TAAR1TRPA1AOC3RIPK1KDM4E | |
| SCHEMBL27847314 | 0.74 | TAAR1 (0.52) | TAAR1TRPA1AOC3RIPK1 | |
| SCHEMBL20414618 | 0.74 | TRPA1 (0.50) | TAAR1TRPA1AOC3RIPK1LMNA | |
| SCHEMBL2418232 | 0.74 | RIPK1 (0.53) | TAAR1TRPA1AOC3RIPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |